| 成小兰，王倩，袁飞飞，崔晓英，张文娟，曹鹏.以临床价值为导向的中药复方转化医学研究思路与方法[J].南京中医药大学学报(社会科学版),2021,37(5):648-653. |
| 以临床价值为导向的中药复方转化医学研究思路与方法 |
| Analysis on the Translational Medicine Research Ideas and Methods of Traditional Chinese Prescription Guided by Clinical Value |
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| DOI： |
| 中文关键词: 关键词:中药复方 转化医学 中医临床 循证医学 临床大数据 |
| 英文关键词: traditional Chinese prescription translational medicine clinical Chinese medicine evidence-based medicine clinical big data |
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| 摘要点击次数: 533 |
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| 中文摘要: |
| 中药复方是中医临床用药的主要形式，也是中医药传承创新发展的重要载体。由于物质基础不清、作用机制不明、质量控制不稳定、循证医学证据缺乏等瓶颈问题，中药复方屡遭质疑，难以获得国际认可，临床应用和产业发展十分受限。如何科学有效开展中药复方基础研究，使其更好为临床服务成了中医药发展迫切需要解决的难题。近年来，转化医学浪潮的兴起为中医药的创新发展带来了新的契机和思路。该文简述了中药复方临床应用和开发面临的困境，转化医学视角下开展复方研究的现状以及存在的主要问题，进一步凝练研究思路与方法，以期为源于中医临床的中药复方转化医学研究提供有益指导。 |
| 英文摘要: |
| Traditional Chinese prescription is the main form of clinical medication of traditional Chinese medicine (TCM)， and also the important carrier of TCM inheritance and innovation. Because of the bottle-neck problems such as unclear chemical basis， unclear function mechanism， unstable quality control and lack of evidence-based medicine，traditional Chinese prescription has been questioned frequently. It is difficult for traditional Chinese prescription to gain international approval， and its clinical application and industrial development are very limited. How to carry out the basic research of traditional Chinese prescription scientifically and effectively for better clinical application has become an urgent problem to be solved in the development of TCM. In recent years，the rising and developing of translational medicine has brought new opportunities and ideas for the innovation and development of TCM. This paper briefly described the difficulties in the clinical application and development of traditional Chinese prescription， discussed the present situation and the main problems in the translational research of TCM， and further condensed the research ideas and methods， with the purpose to provide beneficial guidance for the further research of TCM. |
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