文章摘要
许伟辰,罗子宸,谢彤,狄留庆,郭青,单进军.中药桔梗研究进展及其质量标志物预测初步分析[J].南京中医药大学学报(社会科学版),2021,37(2):294-302.
中药桔梗研究进展及其质量标志物预测初步分析
Advance in Research on Platycodonis Radix and Preliminary Analysis of Its Quality Marker Prediction
  
DOI:
中文关键词: 关键词:桔梗  化学成分  药理活性  质量标志物
英文关键词: Platycodonis Radix  chemical composition  pharmacological activities  Q-marker
基金项目:
作者单位
许伟辰1,罗子宸1, 2,谢彤1,狄留庆2,郭青3,单进军1 1.南京中医药大学中医儿科学研究所江苏省儿童呼吸疾病中医药重点实验室江苏 南京 
210023
2.江苏省中药高效给药系统工程中心江苏 南京 
210023
3.江苏省食品药品监督检验研究院江苏 南京 
210008
 
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中文摘要:
      桔梗是桔梗科植物桔梗Platycodon grandiflorum <\i>(Jacq.) A. DC的干燥根,主要含有皂苷、黄酮、多糖、甾醇和脂肪酸等化学成分,现代研究表明其具有祛痰止咳、抗炎、抗肿瘤、降血糖、抗肥胖、免疫调节等药理作用。从桔梗化学成分、药理作用、体内过程、毒性及溶血性和质量标准等5个方面进行了系统综述,并对其质量标志物进行了探讨,以期为桔梗的进一步研究与开发提供参考。
英文摘要:
      Platycodonis Radix is the dried root of Platycodon grandiflorum <\i>(Jacq.) A. DC, which mainly contains saponins, flavonoids, polysaccharides, sterols and fatty acids. Modern studies have shown that Platycodonis Radix has pharmacological effects such as expectant and cough relieving, anti-inflammatory, anti-tumor, hypoglycemic, anti-obesity and immunoregulation.In this paper, the chemical constituents, pharmacological activities, in vivo<\i> process, toxicity, hemolysis and quality standard of Platycodonis Radix<\i> were systematically reviewed, and the quality markers of Platycodonis Radix were also discussed, in order to provide reference for further research and development of Platycodonis Radix.
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