许伟辰,罗子宸,谢彤,狄留庆,郭青,单进军.中药桔梗研究进展及其质量标志物预测初步分析[J].南京中医药大学学报(社会科学版),2021,37(2):294-302. |
中药桔梗研究进展及其质量标志物预测初步分析 |
Advance in Research on Platycodonis Radix and Preliminary Analysis of Its Quality Marker Prediction |
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DOI: |
中文关键词: 关键词:桔梗 化学成分 药理活性 质量标志物 |
英文关键词: Platycodonis Radix chemical composition pharmacological activities Q-marker |
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中文摘要: |
桔梗是桔梗科植物桔梗Platycodon grandiflorum <\i>(Jacq.) A. DC的干燥根,主要含有皂苷、黄酮、多糖、甾醇和脂肪酸等化学成分,现代研究表明其具有祛痰止咳、抗炎、抗肿瘤、降血糖、抗肥胖、免疫调节等药理作用。从桔梗化学成分、药理作用、体内过程、毒性及溶血性和质量标准等5个方面进行了系统综述,并对其质量标志物进行了探讨,以期为桔梗的进一步研究与开发提供参考。 |
英文摘要: |
Platycodonis Radix is the dried root of Platycodon grandiflorum <\i>(Jacq.) A. DC, which mainly contains saponins, flavonoids, polysaccharides, sterols and fatty acids. Modern studies have shown that Platycodonis Radix has pharmacological effects such as expectant and cough relieving, anti-inflammatory, anti-tumor, hypoglycemic, anti-obesity and immunoregulation.In this paper, the chemical constituents, pharmacological activities, in vivo<\i> process, toxicity, hemolysis and quality standard of Platycodonis Radix<\i> were systematically reviewed, and the quality markers of Platycodonis Radix were also discussed, in order to provide reference for further research and development of Platycodonis Radix. |
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