结合病理生理机制探讨动脉硬化之中医疗护原则

庄昆翰; 庄曜祯

文章摘要

庄昆翰，庄曜祯.结合病理生理机制探讨动脉硬化之中医疗护原则[J].南京中医药大学学报(社会科学版),2019,35(3):356-360.

结合病理生理机制探讨动脉硬化之中医疗护原则

To Investigate the Guideline of Traditional Chinese Medicine Therapy and Care on Arterial Stiffness from the Point of Pathophysiologic Mechanism

DOI：

中文关键词: 关键词：动脉硬化糖化终产物氧化压力中医治疗与护理

英文关键词: 〗Arterial stiffness Advanced glycation end products Oxidative stress Traditional Chinese Medicine Therapy and Nursing

基金项目:

作者	单位
庄昆翰，庄曜祯	1.美国国立卫生研究院国家癌症研究所，马里兰州弗雷德里克〓21702；2.福建医科大学基础医学院,福建福州〓350122；3.澳门镜湖护理学院，澳门〓999078

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中文摘要:

动脉硬化是心血管疾病的主要危险因素。糖化终产物则是导致动脉发生硬化的原因之一，它使得动脉基质中的胶原蛋白产生交互连结，造成动脉壁延展性降低而导致动脉发生硬化。糖化终产物的形成，与氧化压力有很大的关系，而氧化压力又与生活中压力所导致的情志不畅，以及饮食型态、生活习惯有关。对于动脉硬化，中医的治疗与护理原则多以活血化瘀、软坚散结为主，依据辨证的基础，给予相应的治疗及护理措施。

英文摘要:

One of the major risk factors for cardiovascular disease is arterial stiffness. There are several mechanisms associated with the development of arterial stiffness, including the involvement of advanced glycation end products. Arterial stiffness results from altered distensibility of arterial walls and is associated with advanced glycation end productrelated crosslinking of collagen in the artery matrix. Oxidative stress is associated with advanced glycation end products formation and triggered by moodiness, feeding mode, and lifestyle. In TCM and care, the major treatment for arterial stiffness includes activating blood, resolving stasis, softening hardness, and dissipating binds. Depending on the particular syndrome, variations on these major approaches to TCM therapy and related auxiliary nursing care are applied.

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