| 李澈1，蒋峻2*.益心舒胶囊对PCI术后患者生活质量和焦虑、抑郁情绪的影响[J].南京中医药大学学报(社会科学版),2017,33(3):242-244. |
| 益心舒胶囊对PCI术后患者生活质量和焦虑、抑郁情绪的影响 |
| Effects of Yixinshu Capsule on PCI Patients' Postoperative Life Quality， Anxiety and Depression |
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| DOI： |
| 中文关键词: 经皮冠状动脉介入 焦虑 抑郁 益心舒胶囊 生活质量 |
| 英文关键词: percutaneous coronary intervention anxiety depression Yixinshu capsule life quality |
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| 中文摘要: |
| 目的 评价益心舒胶囊对经皮冠状动脉介入（PCI）术后患者的焦虑、抑郁情绪和生活质量改善的有效性和安全性。方法 采用Zung焦虑自评量表(SAS)、抑郁自评量表(SDS)筛选出59例并发焦虑、抑郁情绪的患者，按照2∶1的比例随机分为治疗组(40例)和对照组(19例)，2组均常规给以冠心病二级预防治疗，治疗组加用益心舒胶囊；分别在入院、第1月、第2月、第3月进行HRSD、HAMA、SF-36评分。结果 2组焦虑、抑郁情绪均有明显改善，与治疗前比，HRSD、HAMA评分P<0.05~0.01，治疗组优于对照组（P<0.05~0.01）；治疗组SF-36的生理功能、生理职能、躯体疼痛和一般健康的评分与治疗前比，P<0.05~0.01，对照组生理功能、躯体疼痛、一般健康与治疗前比较，P<0.05~0.01，治疗组优于对照组(P<0.05~0.01)。结论 益心舒胶囊可缓解PCI术后患者焦虑、抑郁情绪，改善其生活质量，无严重的不良反应。 |
| 英文摘要: |
| OBJECTIVE To investigate the postoperative life quality， anxiety and depression conditions of the patients with percutaneous coronary intervention (PCI) as well as its efficacy and safety. METHODS Fifty-nine cases with dual anxiety and depression were selected based on Zung self-rating anxiety scale(SAS) and self-rating depression scale(SDS)， and they were randomly divided into the treatment group (40 cases) and the control group (19 cases) according to the ratio of 2∶1. Both groups were given CHD conventional secondary prevention treatment， with Yixinshu capsule being added to the treatment group. Hamilton Anxiety scale(HRSD)， Hamilton depression scale (HAMA) and SF36 scores were performed during the first， second and third month of their hospitalization. RESULTS The anxiety and depression were both improved significantly in two groups. HRSD and HAMA scores before and after treatment were very different from each other(P<0.05~0.01 )， and the treatment group was better than the control group (P<0.05). In the comparison of scores of physiological function， social function， physical limitations and vitality， physical pain and general health of SF36 before and after treatment， the treatment group was better than the control group (P<0.05). CONCLUSION Yixinshu capsule can relieve patients' anxiety and depression after PCI intervention and improve their life quality， without causing severe adverse events. |
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