池玉梅,杨毅琴,于生.中药材猫爪草有机酸部位药效及组成的研究[J].南京中医药大学学报(社会科学版),2007,23(6):365-. |
中药材猫爪草有机酸部位药效及组成的研究 |
Effect and Composition of Organic Acid of Radix Ranuncuhus Ternati |
投稿时间:2007-06-15 |
DOI: |
中文关键词: 猫爪草 有机酸部位 结核菌 药敏试验 气相色谱-质谱联用技术 |
英文关键词: Radix Ranunculus Ternati organic acid tuberculosis bacteria susceptibility test GC-MS technique |
基金项目:国家自然科学基金(20475027) |
池玉梅 杨毅琴 于生 |
[1]南京中医药大学药学院,江苏南京210046 [2]南京市胸科医院,江苏南京210029 |
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中文摘要: |
目的研究中药材猫爪草有机酸部位的药理作用及化学组成。方法体外结核菌药敏试验和气相色谱-质谱联用技术(GC—MS)。结果药材的有机酸部位具有抗结核作用,并有量效关系;GC—MS分析表明含有多种有机酸成分。结论有机酸部位应为药材的抗结核有效部位之一。 |
英文摘要: |
OBJECTIVE To investigate into the pharmacological effect and chemical composition of the organic acid of Radix Ranunculns Ternati.METHOD In vitro susceptibility test on tuberculosis bacteria and GC-MS technique were used. RESULT The organic acid of the drug had anti-tuberculosis effect with dose-effect relationship. GC-MS analysis indicated that multiple kinds of organic acid existed. CONCLUSION The organic acid of the drug is responsible for its anti-tuberculosis effect. |
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