| 陈佩东,严辉,丁安伟.蒲黄活性部位的药效学筛选研究[J].南京中医药大学学报(社会科学版),2006,22(5):302-303. |
| 蒲黄活性部位的药效学筛选研究 |
| Pharmaceutical Screening of Active Parts of Pollen Typhae |
| 投稿时间：2006-05-18 修订日期：2006-06-20 |
| DOI： |
| 中文关键词: 生蒲黄,炒蒲黄,蒲黄炭,活性部位,药效学 |
| 英文关键词: crude Pollen Typhae,parched Pollen Typhae,carbonized Pollen Typhae,active part,pharmacodynamics |
| 基金项目:国家中医药管理局“十五”国家科技攻关课题(2001BA701A55-27) |
| 陈佩东 严辉 丁安伟 |
| 南京中医药大学药学院 江苏南京210046 |
| 摘要点击次数: 1064 |
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| 中文摘要: |
| 目的确定生蒲黄、炒蒲黄、蒲黄炭止血作用主要活性部位。方法对生蒲黄、炒蒲黄、蒲黄炭按不同溶剂极性及不同化学成分类型提取,以小鼠的止血时间为筛选指标对各部位进行筛选。结果蒲黄及炮制品的乙酸乙酯部位、正丁醇部位、总黄酮部位可明显缩短小鼠凝血时间。结论初步认为总黄酮部位为生蒲黄及其饮片止血作用的主要活性部位。 |
| 英文摘要: |
| OBJECTIVE To determine the main active parts of crude Pollen Typhae,parched Pollen Typhae and carbonized Pollen Typhae.METHOD Extraction was conducted according to different dissolvent heteropolarity and different chemical components and screening conducted with hemostatic time in mice as the index.RESULT The acetic ether portion,n-butanol portion and total flavonoids portion of Pollen Typhae could markedly shorten the coagulate time in mice.CONCLUSION It is preliminarily believed that the total flavonoids portion is the active part of the analgesic effect of crude Pollen Typhae. |
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